Injections are not painful. It is just like being bitten by mosquito. I have been using the word "mosquito" for a thousand times already. I though LIT is just like being bitten by giant mosquito! Ei... it is now swollen and itchy. (24 hours passed LIT).
What is the mechanism of action of LIT? What attacks what?
What produces anti-HLA?
How the CD19 and CD56 counts will decrease?
What will cause TNF-a to drop and how?
Do I need to let those giant mosquitoes bite til they drop? Until one day I get used to their sting?
I am interested to have a visualization of how t-cell, b-cell, macrophages and etc work. Curiosity killed the cat. I will end up in psychiatric ward first before I understand those.
Any idea why LIT should be administered intradermally? "...The skin is an organ of immune defense it contains remarkable numbers of dendritic cells [roughly 10^4/μl (McLellan et al.,1998)] which are the most effective antigen-presenting cells to elicit a primary T-cell response. In blood their concentration is lower (0.1% of leukocytes, i.e. 10/μl)."
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