I have taken Methotrexate 12 years ago. I was lucky that my sacroiliitis activity had went into remission. It has been reported that Methotrexate causes cancer in small population. Scary as it sounds, Methotrexate is actually an anti-cancer drug for treatment of breast, skin and other types of cancers. Methotrexate is an immune suppressant. It induces adenosine which can inhibit tnf-a, interleukin gamma, etc... In the course of treatment, I had suffered drug induced hepatitis. What are the other side effects? Desperation drove me to try Methotrexate. I don't want to think too much. I prayed that Methotrexate would work for me. Thank god, it did.
Ten years ago Tnf-a inhibitors were in experimental phase. I believe it is now available in the market. TNF-a inhibitor is used for treatment of rheumatoid arthritis, ankylosing spondylitis and etc... This drug can cause cancer also. Oh my god, why is it in the market anyway? Same reason as the above. Same approach as the above. If ever needed, I just need to pray that this drug will work on me. How about Imuran- immune suppressant primarily used by kidney transplant patients? Same same!
I am not a cat with nine lives. Question: is it safe for me to get pregnant? My tnf-a:il-10 ratio is a bit above the border. And, delayed cytotoxic hypersensitivity reaction is quite real. I just afraid that my th1 will get out of control when exposed to foreign particles like toxoids and fetus.
Question: forgo the pregnancy dream or try to get pregnant? I have went this far. I guess I should give it a try. If I forgo the pregnancy dream, I may regret this in the future. If I try to get pregnant, I may also regret this in the future. Dumb I do, Dumb I don't.
http://www.webmd.com/rheumatoid-arthritis/news/20041116/rheumatoid-arthritis-drug-linked-to-cancer?page=2
http://www.drugs.com/methotrexate.html
No comments:
Post a Comment