We have different belief with my obgyne and immunologist. What shall we do with the abnormal embryo? My answer is quite simple: discard the abnormal embryo!
My immunologist said I will not exist in this world if my parents did a preimplantation genetic diagnosis on me. I said I am not playing Hitler or God. I just want to embrace science. He held my hands then I cried. I said I don't want a child with juenivile arthritis. His words reverberated til this morning.
Btw, what is the mechanism of the inflammation- how does HLA-B27 promote inflamation? If I look the other side of the coin, seronagativity to HLA-B27 does not mean you will not have ankylosing spondylitis. Seropositivity to HLA-B27 does not necessarily mean a person will have spondyloarthropathy. I need to consider recessive and dominant trait also. Grrr... What is HLA-B27, a dominant or recessive allele? This reminds me of the Mendelian Matrix from high school biology. I somewhat understand his point. I am trying to digest its meaning.
I just detected an inflammatory marker-- HLA-B27 , the allele. I never did the genome sequence in the past. I need to know the gene sequence to probe in my embryos. I guess this is a polymerase chain reaction.
He said I begin to think with the same wavelength. As of this moment, I feel I don't want to do PGD yet. I maybe throwing away life. Ai... Need to reconsider this.
If the belief of doctors here in Philippines that life starts at embryo stage, I guess I will not be able to schedule a geneticist appointment. I told her secretary I want to do PGD in Taiwan. By the way, PGD is banned in the Philippines.
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