What if I had LIT solely on husband's lymphocyte? What if, we share many HLA antigen in common? I will not produce antibody against the common HLA. If I and my husband share many HLA antigen, chances are after 10 x of LIT with husband's lymphocyte the reaction code remains unchanged. Am I correct? What is more important- the reaction code between or the panel reactive antibody score? I guess I don't need to have a positive reaction in each of the serum from the panel reactive antibody. I need positive reaction to my husband's lymphocyte only. Immunologist wants 100% score because they feel high PRA is safe?
Oh, two school of thoughts. First, husband as the sole donor. Second, unrelated donors + husband.
I trust my watch 100%. I wear one watch only, or never at all. Wearing two watches is quite confusing, if both are not synchronized, I don't know which is telling the correct time. It defeats the purpose of wearing a watch. Wearing three watch will be acceptable but quite odd. The logic here is majority wins. Wearing 4 watches is funny.
And... what about my immunologist protocol on the number of donors? Why husband + 3 unrelated donor? My immunologist also wears three watches? He is not happy to wear one watch? Why not 7 donors at a time? I have 3 unrelated donors on first LIT, and another set of 3 unrelated donor on second LIT + husband= 7 donors total? Why not do it together?
"Dear Obgyne,
... She is responding slowly to the LIT. Most likely they share more than one HLA antigens in common...
Regards,
Immunologist"
It is betting time! what will be my reaction code 8-4 , 8-6 , 8-8 or 0-0 on my next LAT-M IgG test? Winners will receive surprise gift.
Back to my very old sentiment... my husband has erectile dysfunction. Limited exposure to sperm creates limited antibody. Therefore I failed in the LAT-M IgG test. I contested I don't have immunologic problem. I don't believe in the PRA thing.
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