T reg and LIT

LIT and T reg
http://www.ncbi.nlm.nih.gov/pubmed/18675967

T reg and B cell suppression
http://www.jimmunol.org/content/175/7/4180.long

T reg and immune tolerance
http://humupd.oxfordjournals.org/content/15/5/517.full

T cells - th1 , th2 and Treg paradigm study in pregnancy
http://onlinelibrary.wiley.com/store/10.1111/j.1600-0897.2010.00852.x/asset/j.1600-0897.2010.00852.x.pdf?v=1&t=hytce7ik&s=36c4dc55ffb1cf629765f97b33e30af8301017bd

LIT seems to be a one size fits all treatment.
- downregulate b cell
- downregulate th1/th2 ratio
- increase the PRA.

Silver bullet? Wait... What is the correlation between panel reactive antibody and immune tolerance? It seems they are unrelated. I wish to share my undying sentiment again... I don't believe I need high PRA to get pregnant. Some patients get pregnant even with zero PRA.

In my lousy immunology perspective, T reg downregulates B cells. B cells are responsible for producing the antibody against husband's HLA. No blocking antibody, no anti-blocking antibody.  T reg also downregulates th1. Therefore, no antibody and t cells will attack the fetus.As long as I have normal count of T reg, I will not have autoimmune disorder and there will be no fetal rejection.

Why am I experiencing  little pain my achilles tendon. Is it autoimmune attack again? Grrr... My t reg should take care of my autoimmune arthropathy. Ai... I will go to test my LAT-M IgG later. Anti-anti- HLA ^.^ What is the correlation of PRA to inflammation (caused by autoimmune disorder)? They are completely unrealated. I cannot explain why do I need LIT. I just choose to believe. I don't want to regret my stubborness to believe in the future.

I never heard LIT to be used as a cure for arthritis. Can LIT control inflammation caused by autoimmune disorder?Because  LIT downregulates of Th1/Th2. Does LIT produce Treg? Wait... Treg sounds interesting if it can prevent autoimmune inflammation.