Eeny meeny miny moe

My Fairy Godmother's patient, who had born a 100% chromosome normal baby, had a Robertsonian translocation. It has 50% success rate. Most of the translocation, I saw in the web, is Robertsonian 45xy tranlocation. My husband has 46xy translocation.

PGS (pre-implantation genetic screening) is not allowed in the Philippines. Does good morphology mean normal chromosome? I guess not. I saw from the web ICSI results in 40% abnormal chromosome. I better consult a geneticist. I saw in the internet the pregnancy chance from 46xy balanced translocation carrier is less than 25%.

Imagine, I successfully retrieved 10 eggs, and 10 eggs were fertilized. What if only 7 are chromosomally normal. How does an embryologist decide which to implant?  Eeny meeny miny moe... Which is the fairest embryo of them all? Two embryo transfer? Quantitative analysis comes into play.What is the chance of picking implanting 2 good embryo? Combin(7,2)/combin(10,2). I almost failed in quantitative analysis back in college. I don't want to scratch my brains and I hate the eeny meeny miny moe!

In reality, the embryologist will be playing an eeny meeny miny moe on my embryo if we don't do PGS. I hope that embryologist is not the one, who did the crappy semen analysis. What if on the first few embryo transfer, all the transfered embryos are with chromosomal abnormalities? It will be a devastating experience for me.

If I do the IVF in the Philippines, can I freeze all the embryo and send samples abroad for testing?  

Not so fast, My Fairy Godmother said she wanted another IUI first before moving on to IVF. IUI again! Why? Grrr... She believed my husband sperm motility and morphology improved a lot. Was that a reverse psychology? I was afraid to have IVF before because I am afraid of OHSS ovarian hyperstimulation syndrome. Now, I am so eager to have ivf, then she wanted to try another round of IUI.