Initially, I was playing Sherlock Holmes. I told my immunologist that maybe I am not allergic to lidocaine because it does not contain benzoate. Benzocaine, tetracaine and sulfasalazine all contains benzoate. Ehem,.. But I am not allergic to benzoate because it is widely used as food preservative. My immunologist just commented that I need to look at its three dimensional structure. If they are IgE mediated, I will also develop allergy from lidocaine even if it doesn't contain benzoate.
I got scared of the fate of my friend she had her preterm labor. I heard she used magnesium sulfate as the first line of defense for contraction. Ouch... sulfa... sulfate? Ehem... google google... I need to brush up my biochemistry. I am not allergic to celecoxib, therefore I am not allergic to the entire class of sulfonamide. Correct? Having a specific drug allergy means it is not IgE mediated. It is triggered by other immune elements.
I guess my new hunch is more logical, benzocaine, tetracaine, lidocaine all contains aniline or aminobenzene. while sulfonamide contains azo.
I suddenly has the fear of anesthesia. Can't I just use propofol and fentanyl? I am scared of allegy. Haha, this reminds me of a hyperventillation once upon a time.
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