Ivig is not a miracle drug

I still keep distance from my obgyne. She asked me to have ivig on my 26th week, how can I refuse without offending her? I really dont feel the need for ivig. I feel she was playing medicine. Ivig is not a miracle drug. I just wrote her a letter. I told her that I will welcome ivig infusion if there is immune rejection. My globulin is high and my albumin/globulin ratio is less than 1. Grrr... I feel the proper authority to give ivig was my immunologist not obgyne. ^.^

Just a backgrounder. I have crp + , 3 days after ivig on my first pregnancy. I had uticaria, fever, chills on the eve of my first delivery after the plasma infusion. How can a forgetful person suggest ivig to me? She told me she had a patient who suffered hair loss because of Imuran. I asked her two times already... Is she 100% sure the hair loss was caused by imuran? I feel her patient had hair loss because of ivig. I believe in the theory of molecular mimicry. Anti- h. Pylori anitbody must be attacking a certain gene that resembles h. Pylori. (Or it triggers autoimmune response.) To me, alopecia is not so scary. I am scared of anti- klebsiella antibody. Some study shows that patients with active anterior uveitis have high titer of anti- klebsiella antibody. Klebsiella has six peptides (or few peptide sequence) that ressembles hla-b27. I am worried about the cross reactivity betweed hla-b27 and anti-klebsiella antibody. I dont want to get uveitis from ivig. My stubborn obgyne yielded. Hehe, shhh... I never discussed my theory with my immunologist. I will try next time.

26 w2d

I never thought I have come this far. So far so good. My congenital anomaly scan was perfect. It confirmed that I am carrying twin boys. Uterine doppler showed high left artery blood flow resistance. My albumin level is lower than the minimum range. It seems that fifteen pcs of amino acida day isnt enough. How many weeks to go ?

I had two bouts of diarrhea last month

I had two bouts of diarrhea last month. The first diarrhea was self limiting. Two soft and loose bowel movements  only but it resulted to systemic inflammation (CRP +). I was given antibiotics. Should I blame this to milk tea or the dimsum?

One or two weeks later, I had another bout of diarrhea. It was watery. I was worried of getting dehydrated. I cannot keep up with the fluid balance. It seems to me that the rate of liquid output was greater than my fluid intake. I was boweling like a toilet flush. Luckily, after seven times it stopped. My fecalysis showed that I had amoebiasis. There were rbc and pus cells in my stool. I was given metronidazole. Few days later, my stool culture had positive growth of citrobacter. Ouch! How can I be so unlucky?  Was it a lab error? Is Citrobacter very virulent? I refused to take another antibiotics.  I fear too much antibiotics will result in yeast infection - candidaiasis. I told my obgyne, I wanted to wait and see.

20w3d

My blood thickens on week 19. All the while, I thought my Kct was behaving well. Ai... Biology is biology. This confirmed that the peak immune response is really week 20-24 ya. I had a Smoflipid last week and I had my LIT last tuesday. Ooops, how much is my cholesterol... 280?

I am excited. But, I am scared to expect. Why am I so pessimistic?

I have back pains. I get tired easily these days. I did not experience these sort of complains in my first pregnancy.

I felt financial pressure as well: choosing school and investing real estate for them, ehem ehem...

Do i need to see a perinatologist?

Why am I reluctant to seek for a second opinion regarding the subchorionic hemorrhage? Do i need to see a perinatologist? What shall be her management plan? Am I reluctant to see another obgyne because I am so attached with my current obgyne?

Is my autoantibodies the root cause of my hemorrhage? I thought my ESR was great. And, the globulin was still within the range ya. But, those data were a week old already. Let us see my updated lab report.

hemorrhage- 7w1d

My black pants were drenched with blood this morning. Had it be other color, I dont know what would be the public reaction? There was a big chunk of blood as well. It was about 3 inch x 2 inch. I was tempted to pick that bloody thin in public urinal for histopath. But, I felt groused. What was that bloody thing?

If the blood comes from outside the cervix, why was it a sudden pour? I was thinking it should be dripping not pouring. I wished my obgyne has checked my vaginal walls yesterday. Maybe we can put topical wound sealant. Should I stop all my pessaries? Should I stop heparin?

I sent my obgyne an sms message informing her about the vaginal bleeding. Luckily, despite of my obgyne's clinic day off today, she was also on her way to her clinic. She examined my vagina today. She said it must be from the cervix. Now, she had spotted the hematoma. The hematoma wasnt there yet yesterday. She asked me to contact my immunologist immediately. She said its immune rejection.

I thought I was extremely lucky this cycle. I thought my pregnancy will be as smooth as the breeze. The blood were storming in my uterus. There was also hematoma.

My babies are safe

Glad to hear that my babies are safe. There was no bleeding inside the uterus. Period! I did not interrogate her much. I dont want her to ask me questions anyway. She just said maybe my tiny blood vessels had bursted. Yeah, perhaps the lacerations were caused by Estrofem and Crinone. I feel prickly sting when I use Estrofem these days. There heat rate has increased to 132 and 144 respectively. So far, so good! Thank god.